Model & assay dataModel characterization

Endometrial organoid profiling

Follow growth and stage-related changes in human endometrial organoids, with epithelial marker profiling to support reproductive biology and drug research.

Model & sampleHuman tissue-derived endometrial organoids

Study setupProliferative, secretory and receptive culture stages

AssaysBright-field, H&E, E-cadherin, Ki67, ER, PR and FOXO1

ESTABLISHMENT & STAGE PHENOTYPES

Stage-specific endometrial phenotypes

Bright-field images of primary establishment and passage of human endometrial organoids — 01
Establishment and passage: serial bright-field images follow tissue-derived organoid formation and growth after passage.
TRiCBIO human endometrial organoid characterization data

H&E, E-cadherin and Ki67 characterization of human endometrial tissue and organoids — 02
Baseline identity: H&E, DAPI, E-cadherin and Ki67 images compare source tissue and organoids for epithelial organization and proliferative state.
TRiCBIO human endometrial organoid characterization data

Serial endometrial organoid morphology across recovery, expansion, differentiation and receptive stages — 03
Stage-dependent morphology: serial imaging within one culture workflow helps define time points for downstream assays.
TRiCBIO human endometrial organoid characterization data

Immunofluorescence for ER, PR and FOXO1 across endometrial organoid stages — 04
Stage-related features: ER, PR and FOXO1 immunofluorescence compares marker distribution across endometrial organoid culture stages.
TRiCBIO human endometrial organoid characterization data

Study application

Serial culture, epithelial identity and ER, PR and FOXO1 profiling connect model establishment with stage-associated phenotypes for hormone-response and candidate studies.

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PROJECT DISCUSSION

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Stage-specific endometrial phenotypes

Study application

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Human endometrial organoid

Safety & toxicology

Multi-organ safety in human organoids

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