
Tumor PDO 2.0
An ALI-based tumor model for studying treatment response alongside source-tissue architecture and immune cells retained from the sample.
Models & products
Compare tumor PDOs, normal-tissue organoids and disease models by project goal, available assays and collaboration format. Browse options for supplied models, TRiCBIO-run studies and custom development.
Start from a common study combination or select up to three models.
Choosing PDO 1.0 or PDO 2.0Featured models · use the filters to explore the full portfolio
0 of 3 models selected for comparison

An ALI-based tumor model for studying treatment response alongside source-tissue architecture and immune cells retained from the sample.

Assess drug-related kidney injury using morphology, nephron markers and molecular readouts; the culture approach is selected by compound mechanism and priority endpoint.

Human lung organoids for pulmonary-injury and candidate studies, combining airway and alveolar cell profiling with changes in tissue morphology.

Organoids from adjacent non-tumor liver tissue for epithelial-biology, drug-exposure and tumor-versus-adjacent-tissue studies.

Study gastric epithelial biology and drug exposure in normal human organoids, with imaging of tissue structure, proliferation and mucin-related markers.

Track morphology and marker expression from primary establishment and passaging through proliferative, secretory and receptive stages, with epithelial-identity profiling throughout.

Human fallopian tube organoids with serial culture morphology and source-tissue/organoid H&E comparison, plus study-specific identity and functional assays.

For inflammatory bowel disease (IBD), established inflammation and barrier assays in mouse intestinal organoids support candidate comparison across morphology, permeability, viability and F-actin/ZO-1; we tailor a human study to the sample and program goal.

Patient-derived breast tumor organoids for single-agent and combination studies, with PDO 2.0 / ALI considered when immune context is relevant.
Explore disease and barrier models, filter by organ, study goal or collaboration format, or discuss a tailored program for specialized tissues and functional endpoints.
PRODUCT CATALOG

A starter kit for PDO 2.0 / ALI recovery and initial culture, with protocol guidance and technical support.

Core reagents for teams with ALI experience or preparing to establish a routine PDO 2.0 culture workflow.

For primary sample processing, organoid establishment, expansion and passaging, with gentle dissociation and workflow guidance matched to the sample.

Configured around model type, cryopreservation scale and post-thaw QC for organoid storage, recovery and biobanking.

For TME-associated cell profiling by flow cytometry or immunofluorescence, with antibody panels matched to the model and assay platform.
Models & products
Compare tumor PDOs, normal-tissue organoids and disease models by project goal, available assays and collaboration format. Browse options for supplied models, TRiCBIO-run studies and custom development.
Start from a common study combination or select up to three models.
Choosing PDO 1.0 or PDO 2.0Featured models · use the filters to explore the full portfolio
0 of 3 models selected for comparison

An ALI-based tumor model for studying treatment response alongside source-tissue architecture and immune cells retained from the sample.

Assess drug-related kidney injury using morphology, nephron markers and molecular readouts; the culture approach is selected by compound mechanism and priority endpoint.

Human lung organoids for pulmonary-injury and candidate studies, combining airway and alveolar cell profiling with changes in tissue morphology.

Organoids from adjacent non-tumor liver tissue for epithelial-biology, drug-exposure and tumor-versus-adjacent-tissue studies.

Study gastric epithelial biology and drug exposure in normal human organoids, with imaging of tissue structure, proliferation and mucin-related markers.

Track morphology and marker expression from primary establishment and passaging through proliferative, secretory and receptive stages, with epithelial-identity profiling throughout.

Human fallopian tube organoids with serial culture morphology and source-tissue/organoid H&E comparison, plus study-specific identity and functional assays.

For inflammatory bowel disease (IBD), established inflammation and barrier assays in mouse intestinal organoids support candidate comparison across morphology, permeability, viability and F-actin/ZO-1; we tailor a human study to the sample and program goal.

Patient-derived breast tumor organoids for single-agent and combination studies, with PDO 2.0 / ALI considered when immune context is relevant.
Explore disease and barrier models, filter by organ, study goal or collaboration format, or discuss a tailored program for specialized tissues and functional endpoints.
PRODUCT CATALOG

A starter kit for PDO 2.0 / ALI recovery and initial culture, with protocol guidance and technical support.

Core reagents for teams with ALI experience or preparing to establish a routine PDO 2.0 culture workflow.

For primary sample processing, organoid establishment, expansion and passaging, with gentle dissociation and workflow guidance matched to the sample.

Configured around model type, cryopreservation scale and post-thaw QC for organoid storage, recovery and biobanking.

For TME-associated cell profiling by flow cytometry or immunofluorescence, with antibody panels matched to the model and assay platform.