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Mesenchymal tumor organoid development

Explore two separate GIST and osteosarcoma studies through culture images, pathology and tissue–PDO marker comparisons.

Model & sampleGIST 3D culture and osteosarcoma PDO research

Study setupGIST culture and pathology comparison; osteosarcoma tissue, PDO and primary-tissue profiling

AssaysBright-field, H&E and Vimentin, Ki67, SOX9 and TP53 profiling

STUDY EVIDENCE

GIST morphology and osteosarcoma marker profiling

GIST morphology and pathology alongside marker profiling from a separate osteosarcoma study.

01GIST · Morphology and pathology

Bright-field, source-tissue and culture H&E compare spindle and mixed spindle/epithelioid patterns.

02Osteosarcoma · Tissue and markers

H&E, Vimentin, Ki67, SOX9 and TP53 panels show identity, proliferation and lineage-associated features.

GIST and osteosarcoma are characterized separately through pathology, culture morphology and relevant markers before candidate and mechanism studies.

Related models and services

PROJECT DISCUSSION

Tell us which model, assay or finding you want to extend. Our scientists will adapt the approach to your candidate, samples and decision point.