01PDO 2.0 model context
Liver-cancer PDO 2.0 culture, histology and identity profiling
Culture morphology, source-tissue/PDO H&E and endothelial- and hepatocyte-related IHC characterize the liver-cancer model.
Study resultsModel and tissue characterization
Liver cancer PDO 2.0: morphology and tissue identity
Culture and source-tissue images, together with hepatic and endothelial marker results, show tissue features of liver cancer PDO 2.0.
Model & sampleTissue-derived liver-tumor PDOs
Study setupModel establishment and tissue characterization; drug or immune conditions configured for follow-on studies
AssaysBright-field, H&E, hepatic/epithelial and endothelial markers; efficacy or immune endpoints configured for follow-on work
STUDY EVIDENCE
Culture morphology and tissue identity in liver-cancer PDO 2.0
Liver-cancer PDO 2.0 culture and tissue profiling, with culture images from a separate conventional HCC PDO.
Study application
Culture, histology and lineage markers guide liver-cancer model selection for efficacy and mechanism studies. Conventional PDO and PDO 2.0 images describe their respective samples.
Related models and services
Explore related models and services
PROJECT DISCUSSION
Discuss a study for your program
Tell us which model features and readouts matter most. Our scientists will recommend the model, QC plan and study endpoints.