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Model & assay dataCase study

HCC PDO and PDO 2.0: culture format and tissue identity

Compare HCC PDO and PDO 2.0 culture morphology alongside source-tissue and marker images to examine model tissue features.

Model & sampleHepatocellular carcinoma PDO and PDO 2.0 with source-tissue comparison
Study setupModel establishment, tissue characterization and treatment conditions selected for the study
AssaysBright-field, whole-mount immunofluorescence, H&E, CD31 and the figure-labelled HEP-1 staining

Study application

HCC culture morphology, whole-mount immunofluorescence and complementary histology and marker panels guide model selection for target-informed efficacy and mechanism studies.

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