Core platform capability
Multimodal assays & QC
Connect tissue imaging, molecular profiling and functional assays to understand model biology and treatment response.
Readouts from separate studies
Choose assays around the research question
Kidney injury, IBD-like inflammation and renal PDO 2.0 studies separately show molecular, barrier, histology and flow results. We select complementary endpoints for your model and candidate.
View imageCisplatin-associated molecular changes: RT-qPCR compares KIM-1, H2AFX and inflammation- and stress-related gene expression in H9-derived kidney organoids.
TRiCBIO H9-derived kidney organoid cisplatin studyView the kidney organoid injury study
View imageBarrier readout | FITC-positive area in matched fields: 0.023% control, 0.944% challenged. One representative field per group.
Study dataView the IBD model and barrier study
View imageModel features and treatment response in RCC PDO 2.0: tissue and PDO images compare morphology, while Annexin V/PI and CD3/CD8 flow cytometry compare cell death and T-cell changes.
TRiCBIO RCC PDO 2.0 study dataView the renal cancer PDO 2.0 studyStudy applications
Choose assays for the program objective
Explain response with more than one endpoint
Receive clear data, images and a study report
Study workflow
Connect model identity to multimodal assays
Select assays for the study objective
Start with the study priority—model identity, efficacy, mechanism or safety—then build the assay panel around it.
Model and batch QC
Use morphology, histology and cell-type markers to establish the model baseline required for the study.
Functional and molecular readouts
Combine viability, apoptosis, barrier, flow, qPCR or secreted readouts so complementary endpoints reinforce interpretation.
Analysis, interpretation and delivery
Bring raw data, analytical methods, QC and interpretation together in a traceable report.
Deliverables
Receive integrated data, images and analysis
- Model and batch QC
- Original images, flow or molecular data
- Analytical methods, statistics and study report
Related models
Select the model by biological context
Assay panels are built around a defined hypothesis, with controls, sample context, model QC and orthogonal confirmation supporting the mechanistic interpretation.
PROJECT DISCUSSION
Build the assay strategy for your study
Share your model, candidate and priority endpoints. We’ll recommend a focused assay panel, define QC and agree the deliverables up front.